How accurate are national stereotypes? A test of different methodological approaches

We compared different methodological approaches in research on the accuracy of national stereotypes that use aggregated mean scores of real people's personality traits as criteria for stereotype accuracy. Our sample comprised 16,713 participants from the Central Europe and 1,090 participants from the Baltic Sea region. Participants rated national stereotypes of their own country using the National Character Survey (NCS) and their personality traits using either the Revised NEO Personality Inventory or the NCS. We examined the effects of different (i) methods for rating of real people (Revised NEO Personality Inventory vs. NCS) and national stereotypes (NCS); (ii) norms for converting raw scores into T‐scores (Russian vs. international norms); and (iii) correlation techniques (intraclass correlations vs. Pearson correlations vs. rank‐order correlations) on the resulting agreement between the ratings of national stereotypes and real people. We showed that the accuracy of national stereotypes depended on the employed methodology. The accuracy was the highest when ratings of real people and national stereotypes were made using the same method and when rank order correlations were used to estimate the agreement between national stereotypes and personality profiles of real people. We propose a new statistical procedure for determining national stereotype accuracy that overcomes limitations of past studies. We provide methodological recommendations applicable to a wider range of cross national stereotype accuracy studies

Direct measurement of the upper critical field in a cuprate superconductor

The upper critical field Hc2 is a fundamental measure of the pairing strength, yet there is no agreement on its magnitude and doping dependence in cuprate superconductors. We have used thermal conductivity as a direct probe of Hc2 in the cuprates YBa2Cu3Oy and YBa2Cu4O8 to show that there is no vortex liquid at T = 0, allowing us to use high-field resistivity measurements to map out the doping dependence of Hc2 across the phase diagram. Hc2(p) exhibits two peaks, each located at a critical point where the Fermi surface undergoes a transformation. The condensation energy obtained directly from Hc2, and previous Hc1 data, undergoes a 20-fold collapse below the higher critical point. These data provide quantitative information on the impact of competing phases in suppressing superconductivity in cuprates.Comment: to appear in Nature Communications; Supplementary Information file available upon reques

Progressive skin fibrosis is associated with a decline in lung function and worse survival in patients with diffuse cutaneous systemic sclerosis in the European Scleroderma Trials and Research (EUSTAR) cohort.

Objectives To determine whether progressive skin fibrosis is associated with visceral organ progression and mortality during follow-up in patients with diffuse cutaneous systemic sclerosis (dcSSc). Methods We evaluated patients from the European Scleroderma Trials and Research database with dcSSc, baseline modified Rodnan skin score (mRSS) ≥7, valid mRSS at 12±3 months after baseline and ≥1 annual follow-up visit. Progressive skin fibrosis was defined as an increase in mRSS >5 and ≥25% from baseline to 12±3 months. Outcomes were pulmonary, cardiovascular and renal progression, and all-cause death. Associations between skin progression and outcomes were evaluated by Kaplan-Meier survival analysis and multivariable Cox regression. Results Of 1021 included patients, 78 (7.6%) had progressive skin fibrosis (skin progressors). Median follow-up was 3.4 years. Survival analyses indicated that skin progressors had a significantly higher probability of FVC decline ≥10% (53.6% vs 34.4%; p<0.001) and all-cause death (15.4% vs 7.3%; p=0.003) than non-progressors. These significant associations were also found in subgroup analyses of patients with either low baseline mRSS (≤22/51) or short disease duration (≤15 months). In multivariable analyses, skin progression within 1 year was independently associated with FVC decline ≥10% (HR 1.79, 95% CI 1.20 to 2.65) and all-cause death (HR 2.58, 95% CI 1.31 to 5.09). Conclusions Progressive skin fibrosis within 1 year is associated with decline in lung function and worse survival in dcSSc during follow-up. These results confirm mRSS as a surrogate marker in dcSSc, which will be helpful for cohort enrichment in future trials and risk stratification in clinical practice

Geographical and temporal distribution of SARS-CoV-2 clades in the WHO European Region, January to June 2020

We show the distribution of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) genetic clades over time and between countries and outline potential genomic surveillance objectives. We applied three genomic nomenclature systems to all sequence data from the World Health Organization European Region available until 10 July 2020. We highlight the importance of real-time sequencing and data dissemination in a pandemic situation, compare the nomenclatures and lay a foundation for future European genomic surveillance of SARS-CoV-2

Flächendeckende Bahnplanung in vollständig, teilweise oder nicht bekannten Umgebungen

Es wird die Aufgabe der vollständigen räumlichen Abdeckung von Regionen in durch mobile Roboter betrachtet. Da-bei können die Regionen in vollständig, teilweise oder nicht bekannten Umgebungen liegen. Zur Lösung wird ein Verfahren aus der Computer-grafik zum Füllen von Bildregionen zugrunde gelegt. Das Verfahren hat eine lokale Sichtweise und läßt somit den Einsatz von Sensordaten und das Auftreten von unvorhergesehenen Hindernissen zu. Die Regionen können durch Karten off-line vorgegeben sein oder durch Sensordaten on-line aufgebaut werden. Dennoch ist eine vollständige und genau einma-lige Flächenbearbeitung garantiert. Dies wird an Beispielen in einer graphischen Visualisierung der Realzeit-Steuerung des Roboters validiert

Flächendeckende Bahnplanung in vollständig, teilweise oder nicht bekannten Umgebungen

Es wird die Aufgabe der vollständigen räumlichen Abdeckung von Regionen in durch mobile Roboter betrachtet. Da-bei können die Regionen in vollständig, teilweise oder nicht bekannten Umgebungen liegen. Zur Lösung wird ein Verfahren aus der Computer-grafik zum Füllen von Bildregionen zugrunde gelegt. Das Verfahren hat eine lokale Sichtweise und läßt somit den Einsatz von Sensordaten und das Auftreten von unvorhergesehenen Hindernissen zu. Die Regionen können durch Karten off-line vorgegeben sein oder durch Sensordaten on-line aufgebaut werden. Dennoch ist eine vollständige und genau einma-lige Flächenbearbeitung garantiert. Dies wird an Beispielen in einer graphischen Visualisierung der Realzeit-Steuerung des Roboters validiert

Rediscovering Psilocybin as an Antidepressive Treatment Strategy

There has recently been a renewal of interest in psychedelic research on the use of psilocybin in psychiatric treatment and, in particular, for the treatment of major depressive disorder (MDD). Several state-of-the-art studies have provided new insight into the mechanisms of action of psilocybin and its therapeutic potential. Nevertheless, many questions remain unanswered. With this review, we provide an overview of the current state of research on the potential mechanisms of psilocybin, its antidepressant potential, and the associated risks and adverse effects, to provide an update on a controversial topic discussed in psychopharmacology. A database search was conducted in Medline including articles on psilocybin over the period of the last 20 years. Despite the promising progress in understanding the mechanisms of psilocybin, the exact antidepressive mechanism and the role of the psychedelic experience remain elusive. The studies included in this review found high treatment effect sizes for psilocybin as an antidepressant. However, the results must be regarded as preliminary due to several limitations. Although the current studies observed no severe adverse events, several questions regarding safety and utility remain and must be subject of future research